When it opened at 303 Rocky Run in March 1998, John Harvard’s Brandywine Hundred location became the 14th owned by the New England-based brewpub chain. The 8,401-square-foot restaurant and brewery produced exceptional beers and was popular during its 7½-year run. Sales did not meet the corporation’s expectations and the location closed in September 2005.
The original John Harvard’s Brewery & Ale House in Harvard Square, Cambridge, MA ceased brewing in 2015 and closed altogether in 2019. The Framingham, MA location, the last of Harvard’s franchised breweries, closed in 2020.